KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DYRK2
All Species:
16.67
Human Site:
S98
Identified Species:
26.19
UniProt:
Q92630
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92630
NP_003574.1
601
66652
S98
Q
Q
L
F
E
D
N
S
N
K
R
T
V
L
T
Chimpanzee
Pan troglodytes
XP_509205
601
66595
S98
Q
Q
L
F
E
D
N
S
N
K
R
T
V
L
T
Rhesus Macaque
Macaca mulatta
XP_001117134
601
66643
S98
Q
Q
L
F
E
D
N
S
N
K
R
T
V
L
T
Dog
Lupus familis
XP_538273
601
66656
S98
Q
Q
L
F
E
D
N
S
N
K
R
T
V
L
T
Cat
Felis silvestris
Mouse
Mus musculus
Q5U4C9
599
66538
P121
K
T
G
L
P
G
V
P
E
R
Q
L
E
S
I
Rat
Rattus norvegicus
Q4V8A3
586
65492
N107
L
Q
S
D
G
V
S
N
S
E
K
S
S
P
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511087
546
60615
Q108
T
P
E
Q
A
V
K
Q
Y
L
Q
K
L
T
A
Chicken
Gallus gallus
Q5ZIU3
526
59419
F95
Y
M
Q
K
L
T
T
F
E
H
N
E
I
F
G
Frog
Xenopus laevis
NP_001088793
567
63329
T105
K
S
L
D
S
S
G
T
S
K
S
S
E
S
S
Zebra Danio
Brachydanio rerio
NP_001038298
587
65453
G108
L
T
P
V
G
R
A
G
L
A
M
P
E
K
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P83102
828
92722
L152
K
D
V
P
G
L
F
L
R
T
I
S
E
N
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_001023208
796
87422
K337
Q
S
I
G
G
P
N
K
H
L
S
A
S
H
S
Sea Urchin
Strong. purpuratus
XP_799140
561
63192
A99
N
G
H
L
S
H
D
A
N
A
L
P
D
V
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P51566
467
54180
K36
I
V
D
K
R
P
R
K
R
P
R
L
T
W
D
Baker's Yeast
Sacchar. cerevisiae
P14680
807
91227
S245
R
L
S
A
Y
P
P
S
T
S
P
P
L
Q
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
99.6
98.3
N.A.
97
59.7
N.A.
78.6
81.3
64.5
83.6
N.A.
43.3
N.A.
45.7
63.7
Protein Similarity:
100
98.8
99.8
99
N.A.
98.5
71.8
N.A.
83
84.5
75
89.8
N.A.
54.9
N.A.
55.6
73.5
P-Site Identity:
100
100
100
100
N.A.
0
6.6
N.A.
0
0
13.3
0
N.A.
0
N.A.
13.3
6.6
P-Site Similarity:
100
100
100
100
N.A.
20
46.6
N.A.
13.3
6.6
46.6
0
N.A.
26.6
N.A.
33.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.3
27.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.6
41.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
7
0
7
7
0
14
0
7
0
0
14
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
7
14
0
27
7
0
0
0
0
0
7
0
7
% D
% Glu:
0
0
7
0
27
0
0
0
14
7
0
7
27
0
0
% E
% Phe:
0
0
0
27
0
0
7
7
0
0
0
0
0
7
0
% F
% Gly:
0
7
7
7
27
7
7
7
0
0
0
0
0
0
7
% G
% His:
0
0
7
0
0
7
0
0
7
7
0
0
0
7
0
% H
% Ile:
7
0
7
0
0
0
0
0
0
0
7
0
7
0
7
% I
% Lys:
20
0
0
14
0
0
7
14
0
34
7
7
0
7
7
% K
% Leu:
14
7
34
14
7
7
0
7
7
14
7
14
14
27
0
% L
% Met:
0
7
0
0
0
0
0
0
0
0
7
0
0
0
0
% M
% Asn:
7
0
0
0
0
0
34
7
34
0
7
0
0
7
0
% N
% Pro:
0
7
7
7
7
20
7
7
0
7
7
20
0
7
7
% P
% Gln:
34
34
7
7
0
0
0
7
0
0
14
0
0
7
7
% Q
% Arg:
7
0
0
0
7
7
7
0
14
7
34
0
0
0
0
% R
% Ser:
0
14
14
0
14
7
7
34
14
7
14
20
14
14
20
% S
% Thr:
7
14
0
0
0
7
7
7
7
7
0
27
7
7
27
% T
% Val:
0
7
7
7
0
14
7
0
0
0
0
0
27
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% W
% Tyr:
7
0
0
0
7
0
0
0
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _